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Iratxe Madarieta (female) obtained her degree in Biological Sciences in 1999 and her PhD in chemistry in 2012 by the University of the Basque Country. She is senior researcher in the Biomaterials Area-Health Division of TECNALIA with more than 20 years of experience in the research of Biomaterials. Firstly focused on the biocompatibility studies of synthetic materials and developing new advanced materials with therapeutic and regenerative activity mainly in 2D and 3D cellular models. During this period, she achieved a new corneal implant with therapeutic capacity as an inventor of a patent ("Implantable optical system, method for developing it and applications" WO2008020087). In the last 10 years she has focused her research on the investigation and development of biologic scaffold materials particularly adipose tissue extracellular matrix ones. These investigations have led her to obtain a new patent ("Method for producing a decellularized tissue matrix" WO2016EP82849). She focused her research on the developmenet and application of ECM-derived biomaterials (adipose, cartilage, msucle..) fo in vitro microtissue models, organ-on-a-chip devices, electrophysiology and regenerative medicine. She is currently working on the application of the new biomaterial resulting from the patented method for in vitro tissue models and tissue bioprinting technologies. As a result of his latest research, he has demonstrated the ability of the material to bioprint cells and tissues and to induce stem cell differentiation, research that has allowed him to publish more than 10 publications in the last 5 years.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Validation of an in vitro muscle platform to evaluate myogenesis and calcium handling in control and dystrophic human myotubes
Mosqueira-Martín, L., Prendes-García, C., Vesga-Castro, C., Marco-Moreno, P., Irastorza, A., Izeta, A., Madarieta, I., Martí-Carrera, I., Paredes, J., de Munain, A. L. & Vallejo-Illarramendi, A., Dec 2026, In: Scientific Reports. 16, 1, 1891.Research output: Contribution to journal › Article › peer-review
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Adipose tissue-derived ECM hydrogels as a 3D platform for neural differentiation and brain diseases
Stampouli, K., Papadimitriou, L., García-Lizarribar, A., Madarieta, I., Olalde, B. & Ranella, A., 2025, (Accepted/In press) In: Materials Advances.Research output: Contribution to journal › Article › peer-review
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Generation of humanized bone for disease modeling using porcine adipose tissue-derived extracellular matrix scaffolds and human dental pulp stem cells
Madarieta, I., Luzuriaga, J., Salvador-Moya, J., Pardo-Rodríguez, B., García-Gallastegui, P., García-Urkia, N., Irastorza, I., Fernandez-San-Argimiro, F. J., Uribe-Etxebarria, V., Jiménez-Rojo, L., Unda, F., Olalde, B., Pineda, J. R. & Ibarretxe, G., Jan 2025, Animal Models of Disease - Part D. Academic Press Inc., p. 59-76 18 p. (Methods in Cell Biology; vol. 197).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Biocompatible adipose extracellular matrix and reduced graphene oxide nanocomposite for tissue engineering applications
Verstappen, K., Klymov, A., Cicuéndez, M., da Silva, D. M., Barroca, N., Fernández-San-Argimiro, F. J., Madarieta, I., Casarrubios, L., Feito, M. J., Diez-Orejas, R., Ferreira, R., Leeuwenburgh, S. C. G., Portolés, M. T., Marques, P. A. A. P. & Walboomers, X. F., Jun 2024, In: Materials Today Bio. 26, 101059.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus) -
Functionality of macrophages encapsulated in porcine decellularized adipose matrix hydrogels and interaction with Candida albicans
Cicuéndez, M., García-Lizarribar, A., Casarrubios, L., Feito, M. J., Fernández-San-Argimiro, F. J., García-Urkia, N., Murua, O., Madarieta, I., Olalde, B., Diez-Orejas, R. & Portolés, M. T., May 2024, In: Biomaterials Advances. 159, 213794.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)
Thesis
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Desarrollo de un nuevo material terapéutico para el tratamiento de desórdenes corneales.
Madarieta Pardo, I. (Author), 2013Doctoral thesis: Doctoral Thesis
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