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Leire Goikoetxea has a degree in Biochemistry from the University of the Basque Country (UPV / EHU 2000) and a Master in Innovation and Technology Management (2003). She joined Tecnalia in 2000, collaborating in research projects in Tisular Engineering, focusing her activity on the evaluation of the biocompatibility of biomaterials in contact with mammalian cells, and which has continued until today in the Biomaterials group of the Division of Health of Tecnalia.
She is an expert in cell cultures and in the biological characterization of biomaterials, through the evaluation of the cellular response in vitro (analysis of the toxicity of materials in cells, analysis of adhesion, proliferation and cell death, analysis of the expression of specific biomolecules of the cell line used, analysis of the content of the genetic material ...) using spectrophotometric and fluorometric techniques, enzymatic techniques and immunofluorescence techniques, among others.
In addition, she has collaborated in projects related to drug delivery and transport systems, as well as in projects related to the functionalization of surfaces for in vitro diagnostic applications. Moreover, she has participated in the development of LOC devices for the detection of disease biomarkers in different biofluids (blood plasma, tears…). Her research activity is reflected in international scientific articles, and in numerous contributions to congress.
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Biological response of laser macrostructured and oxidized titanium alloy: An in vitro and in vivo study
Paz, M. D., Iñaki Álava, J., Goikoetxea, L., Chiussi, S., Díaz-Güemes, I., Usón, J., Sánchez, F. & León, B., Sept 2011, In: Journal of Applied Biomaterials and Biomechanics. 9, 3, p. 214-222 9 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition
Paz, M. D., Chiussi, S., González, P., Serra, J., León, B., Goikoetxea, L. & Alava, J. I., 2008, In: Key Engineering Materials. 361-363 I, p. 625-628 4 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Nanozirconia partially coated MWNT: Nanostructural characerization and cytotoxicity and lixivation study
Garmendia, N., Bilbao, L., Muñoz, R., Goikoetxea, L., García, A., Bustero, I., Olalde, B., Garagorri, N. & Obieta, I., 2008, In: Key Engineering Materials. 361-363 II, p. 775-778 4 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Interaction of engineered surfaces with the living world: Ion implantation vs. osseointegration
Braceras, I., Alava, J. I., Goikoetxea, L., de Maeztu, M. A. & Onate, J. I., 5 Aug 2007, In: Surface and Coatings Technology. 201, 19-20 SPEC. ISS., p. 8091-8098 8 p.Research output: Contribution to journal › Review article › peer-review
35 Citations (Scopus) -
Carbon nanotubes for biological devices
García, A., Bustero, I., Muñoz, R., Goikotxea, L. & Obieta, I., May 2006, In: Physica Status Solidi (A) Applications and Materials Science. 203, 6, p. 1117-1123 7 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)