Artificial Intelligence and Wearable Technologies for Upper Limb Neurorehabilitation

  • Ilaria Siviero
  • , Nicola Valè
  • , Gloria Menegaz
  • , Ander Ramos-Murguialday
  • , Silvia Francesca Storti*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Non-invasive neural interfaces (NIs) are increasingly investigated in upper limb neurorehabilitation, where they exploit biosignals, such as electroencephalography (EEG) and electromyography (EMG), to decode motor intentions using artificial intelligence (AI). Yet, traditional systems are complex and difficult to use outside the clinic. Wearable devices have the potential for innovative neurorehabilitation solutions thanks to their comfort, easy-to-use and long-term monitoring. However, current AI approaches require adaptation to the technical constraints of wearable devices, and the related state-of-the-art is not clearly explained and summarized. In this work, a systematic literature review on 51 studies was conducted analyzing them according to five important concepts: biosignals, wearable devices, AI-driven methods, upper limb, and clinical applications. The review highlights methodological heterogeneity, a variety of wearable sensor configurations, and open challenges related to accuracy, robustness, and clinical validation. Finally, we discuss how explainable AI (XAI) and generative AI (GenAI) may contribute to improve the interpretability and personalization of future neurorehabilitation systems.

Original languageEnglish
Pages (from-to)732-749
Number of pages18
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Volume34
DOIs
Publication statusPublished - 2026

Keywords

  • Artificial intelligence
  • rehabilitation
  • telemedicine
  • upper limb
  • wearable sensors

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