@article{1ee2b990252444b88bee6ab303b7c9d3,
title = "Catalytic asymmetric alkylation of aryl heteroaryl ketones",
abstract = "Tertiary diarylmethanols are highly bioactive structural motifs. A new strategy to access chiral tertiary diarylmethanols through copper-catalyzed direct alkylation of (di)(hetero)aryl ketones by using Grignard reagents was developed. The low reactivity and the similarity of the enantiotopic faces of bisaromatic ketones were partially overcome, which resulted in moderate to good yields and enantioselectivities.",
keywords = "Addition reactions, Alcohols, Alkylation, Asymmetric catalysis, Diarylmethanols, Synthetic methods",
author = "Pablo Ortiz and {Del Hoyo}, {Ana M.} and Harutyunyan, {Syuzanna R.}",
note = "Publisher Copyright: {\textcopyright} 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2015",
month = jan,
doi = "10.1002/ejoc.201403297",
language = "English",
volume = "2015",
pages = "72--76",
journal = "European Journal of Organic Chemistry",
issn = "1434-193X",
publisher = "Wiley-VCH Verlag",
number = "1",
}