Circuit Modeling of rGO-doped Scaffolds for Spinal Cord Regeneration Based on Transient and xAC Analyses

Latifah Al-Maghrabi, Patricia Martins, Daniela Silva, Guilherme Gil, Nathalie Barroca, Olatz Murua, Beatriz Olalde, Luis Alves, Paulo Pedreiras, Pedro Fonseca, Philip Leduc, Paula Marques*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Circuit modeling of scaffolds based on porcine adipose decellularized extracellular matrix (adECM) doped with reduced graphene oxide (rGO) for spinal cord regeneration is presented. The characteristics of the scaffolds capped with silver electrodes were studied in an aqueous medium through transient and AC analyses. In addition, cyclic voltammetry (CV) plots were obtained. The transient measurements were done using a custom current driver while the CV and AC measurements were obtained with an external impedance analyzer. The results revealed that incorporating rGO reduced the series resistance and the impedance at low frequencies of the scaffold.

Original languageEnglish
Title of host publicationIEEE International Symposium on Circuits and Systems, ISCAS 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1087-1091
Number of pages5
ISBN (Electronic)9781665484855
DOIs
Publication statusPublished - 2022
Event2022 IEEE International Symposium on Circuits and Systems, ISCAS 2022 - Austin, United States
Duration: 27 May 20221 Jun 2022

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
Volume2022-May
ISSN (Print)0271-4310

Conference

Conference2022 IEEE International Symposium on Circuits and Systems, ISCAS 2022
Country/TerritoryUnited States
CityAustin
Period27/05/221/06/22

Keywords

  • SCI
  • electrical stimulation
  • injury
  • neural recovery
  • regeneration
  • scaffold

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