Evaluation of the improvement of an LMR-based planar biosensor by depositing a low refractive index intermediate thin-film

  • M. Benitez*
  • , P. Zubiate
  • , A. B. Socorro
  • , I. Del Villar
  • , I. R. Matias
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Planar waveguide configuration is a good alternative to lossy mode resonance (LMR) based fiber sensors, but it requires many efforts in order to enhance resonance parameters. An interesting approach to this purpose consists of depositing a low refractive index intermediate layer. This reduces the spectral width of the resonance and improves the figure of merit (FOM). In this work, the results when detecting anti-IgG by using three biosensors fabricated with and without a SiO2 intermediate layer have been compared. LMRs using a TiO2 thin-film are generated so that their TM polarization component is located within the visible range and their TE polarization component is located in the NIR. The biosensor with the highest FOM (0.003 ppm-1) has been the one fabricated using an intermediate layer and locating the LMR with TM component in the visible range. Moreover, this structure shows a limit of detection (LoD) of 0.02 μ g /ml, the lowest value achieved, and what is more important, its transition to a real application.

Original languageEnglish
Title of host publication2023 IEEE BioSensors Conference, BioSensors 2023 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350346046
DOIs
Publication statusPublished - 2023
Externally publishedYes
Event1st Annual IEEE BioSensors Conference, BioSensors 2023 - London, United Kingdom
Duration: 30 Jul 20231 Aug 2023

Publication series

Name2023 IEEE BioSensors Conference, BioSensors 2023 - Proceedings

Conference

Conference1st Annual IEEE BioSensors Conference, BioSensors 2023
Country/TerritoryUnited Kingdom
CityLondon
Period30/07/231/08/23

Keywords

  • figure of merit
  • lossy mode resonance
  • optical biosensor
  • planar waveguide
  • spectral width

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