Fiber optic glucose biosensor

Ignacio Del Villar; Ignacio R. Matias; Francisco J. Arregui; Jesus M. Corres

doi:10.1117/1.2360174

Fiber optic glucose biosensor

Ignacio Del Villar^*
, Ignacio R. Matias
, Francisco J. Arregui
, Jesus M. Corres

^*Corresponding author for this work

Public University of Navarre

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

A fiber-optic biosensor for glucose concentration detection has been designed, based on electrostatic self-assembly. The end face of a multimode fiber is coated with poly(allylamine hydrochloride) in combination with Prussian blue and the enzyme glucose oxidase. The glucose concentration that can be measured ranges between 0.06 and 2 mM. The initial velocity of change of the output blosensor signal has been found to be linear in the glucose concentration. The sensor recovers after immersion in ascorbic acid. The pH values analyzed range between 5 and 7. The sensitivity of the device has been increased by adjusting the number of bilayers and by adding some capping bilayers at the end of the structure.

Original language	English
Article number	104401
Journal	Optical Engineering
Volume	45
Issue number	10
DOIs	https://doi.org/10.1117/1.2360174
Publication status	Published - Oct 2006
Externally published	Yes

Keywords

Glucose biosensor
Glucose oxidase
Layer-by-layer self-assembly
Optical fiber sensor
Prussian blue

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10.1117/1.2360174

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title = "Fiber optic glucose biosensor",

abstract = "A fiber-optic biosensor for glucose concentration detection has been designed, based on electrostatic self-assembly. The end face of a multimode fiber is coated with poly(allylamine hydrochloride) in combination with Prussian blue and the enzyme glucose oxidase. The glucose concentration that can be measured ranges between 0.06 and 2 mM. The initial velocity of change of the output blosensor signal has been found to be linear in the glucose concentration. The sensor recovers after immersion in ascorbic acid. The pH values analyzed range between 5 and 7. The sensitivity of the device has been increased by adjusting the number of bilayers and by adding some capping bilayers at the end of the structure.",

keywords = "Glucose biosensor, Glucose oxidase, Layer-by-layer self-assembly, Optical fiber sensor, Prussian blue",

author = "\{Del Villar\}, Ignacio and Matias, \{Ignacio R.\} and Arregui, \{Francisco J.\} and Corres, \{Jesus M.\}",

year = "2006",

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doi = "10.1117/1.2360174",

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journal = "Optical Engineering",

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AU - Del Villar, Ignacio

AU - Matias, Ignacio R.

AU - Arregui, Francisco J.

AU - Corres, Jesus M.

PY - 2006/10

Y1 - 2006/10

N2 - A fiber-optic biosensor for glucose concentration detection has been designed, based on electrostatic self-assembly. The end face of a multimode fiber is coated with poly(allylamine hydrochloride) in combination with Prussian blue and the enzyme glucose oxidase. The glucose concentration that can be measured ranges between 0.06 and 2 mM. The initial velocity of change of the output blosensor signal has been found to be linear in the glucose concentration. The sensor recovers after immersion in ascorbic acid. The pH values analyzed range between 5 and 7. The sensitivity of the device has been increased by adjusting the number of bilayers and by adding some capping bilayers at the end of the structure.

AB - A fiber-optic biosensor for glucose concentration detection has been designed, based on electrostatic self-assembly. The end face of a multimode fiber is coated with poly(allylamine hydrochloride) in combination with Prussian blue and the enzyme glucose oxidase. The glucose concentration that can be measured ranges between 0.06 and 2 mM. The initial velocity of change of the output blosensor signal has been found to be linear in the glucose concentration. The sensor recovers after immersion in ascorbic acid. The pH values analyzed range between 5 and 7. The sensitivity of the device has been increased by adjusting the number of bilayers and by adding some capping bilayers at the end of the structure.

KW - Glucose biosensor

KW - Glucose oxidase

KW - Layer-by-layer self-assembly

KW - Optical fiber sensor

KW - Prussian blue

UR - https://www.scopus.com/pages/publications/33846045313

U2 - 10.1117/1.2360174

DO - 10.1117/1.2360174

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AN - SCOPUS:33846045313

SN - 0091-3286

VL - 45

JO - Optical Engineering

JF - Optical Engineering

IS - 10

M1 - 104401

ER -

Fiber optic glucose biosensor

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Keywords

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