Fiber-optic immunosensor based on lossy mode resonances induced by indium tin oxide thin-films

  • Abian B. Socorro
  • , Ignacio Del Villar
  • , Jesus M. Corres
  • , Francisco J. Arregui
  • , Ignacio R. Matias

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

A novel immunosensor based on lossy mode resonances (LMRs) induced in optical fibers is developed in this contribution. Indium tin oxide (ITO) is sputtered on the optical substrate to generate an LMR in the transmission spectrum. Type G immunoglobulins (IgGs) are then attached to the ITO-coated fiber using (3-glycidyloxypropyl)trimethoxysilane (GPTMS). A phosphate buffer saline solution containing anti-IgGs is used to detect the biological reactions. The presented device is capable of detecting anti-IgG concentrations up to 10 nM. These results will permit the fabrication of biosensors based on a covalent attachment of bioreceptors over an LMR inducing thin-film.

Original languageEnglish
Title of host publicationIEEE Sensors, SENSORS 2016 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479982875
DOIs
Publication statusPublished - 5 Jan 2016
Externally publishedYes
Event15th IEEE Sensors Conference, SENSORS 2016 - Orlando, United States
Duration: 30 Oct 20162 Nov 2016

Publication series

NameProceedings of IEEE Sensors
Volume0
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229

Conference

Conference15th IEEE Sensors Conference, SENSORS 2016
Country/TerritoryUnited States
CityOrlando
Period30/10/162/11/16

Keywords

  • immunosensors
  • indium tin oxide
  • lossy mode resonances
  • opticalfiber
  • thin-films

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