In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition

M. D. Paz; S. Chiussi; P. González; J. Serra; B. León; L. Goikoetxea; J. I. Alava

In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition

M. D. Paz, S. Chiussi, P. González, J. Serra, B. León, L. Goikoetxea, J. I. Alava

Biomaterials

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Human fetal osteoblast (hFOB) cell adhesion and cell proliferation studies have been performed on laser macrostructured titanium alloy substrates with and without pulsed laser deposited thin calcium phosphate coating. Coating was only 100 nm thick. The combined laser processing approach for modification of titanium alloy surfaces has yielded improved cell adhesion and proliferation of cells. Alkaline phosphatase activity was very significantly higher in the coated samples suggesting a intense stimuli of early osteoblast differentiation that should lead to improve bone growth on these surfaces.

Original language	English
Pages (from-to)	625-628
Number of pages	4
Journal	Key Engineering Materials
Volume	361-363 I
Publication status	Published - 2008

Keywords

Hydroxyapatite
In vitro tests
Macrostructure
Pulsed laser deposition
Ti6l4V

Cite this

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title = "In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition",

abstract = "Human fetal osteoblast (hFOB) cell adhesion and cell proliferation studies have been performed on laser macrostructured titanium alloy substrates with and without pulsed laser deposited thin calcium phosphate coating. Coating was only 100 nm thick. The combined laser processing approach for modification of titanium alloy surfaces has yielded improved cell adhesion and proliferation of cells. Alkaline phosphatase activity was very significantly higher in the coated samples suggesting a intense stimuli of early osteoblast differentiation that should lead to improve bone growth on these surfaces.",

keywords = "Hydroxyapatite, In vitro tests, Macrostructure, Pulsed laser deposition, Ti6l4V",

author = "Paz, {M. D.} and S. Chiussi and P. Gonz{\'a}lez and J. Serra and B. Le{\'o}n and L. Goikoetxea and Alava, {J. I.}",

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T1 - In vitro evaluation of combined laser processing on Ti6Al4V discs

T2 - Macrostructuring and pulsed laser deposition

AU - Paz, M. D.

AU - Chiussi, S.

AU - González, P.

AU - Serra, J.

AU - León, B.

AU - Goikoetxea, L.

AU - Alava, J. I.

PY - 2008

Y1 - 2008

N2 - Human fetal osteoblast (hFOB) cell adhesion and cell proliferation studies have been performed on laser macrostructured titanium alloy substrates with and without pulsed laser deposited thin calcium phosphate coating. Coating was only 100 nm thick. The combined laser processing approach for modification of titanium alloy surfaces has yielded improved cell adhesion and proliferation of cells. Alkaline phosphatase activity was very significantly higher in the coated samples suggesting a intense stimuli of early osteoblast differentiation that should lead to improve bone growth on these surfaces.

AB - Human fetal osteoblast (hFOB) cell adhesion and cell proliferation studies have been performed on laser macrostructured titanium alloy substrates with and without pulsed laser deposited thin calcium phosphate coating. Coating was only 100 nm thick. The combined laser processing approach for modification of titanium alloy surfaces has yielded improved cell adhesion and proliferation of cells. Alkaline phosphatase activity was very significantly higher in the coated samples suggesting a intense stimuli of early osteoblast differentiation that should lead to improve bone growth on these surfaces.

KW - Hydroxyapatite

KW - In vitro tests

KW - Macrostructure

KW - Pulsed laser deposition

KW - Ti6l4V

UR - http://www.scopus.com/inward/record.url?scp=38149094345&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:38149094345

SN - 1013-9826

VL - 361-363 I

SP - 625

EP - 628

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

In vitro evaluation of combined laser processing on Ti6Al4V discs: Macrostructuring and pulsed laser deposition

Abstract

Keywords

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