Nanocluster-antibody conjugates and uses thereof

Nerea Briz Iceta; Veronica Mora Sanz

Nanocluster-antibody conjugates and uses thereof

Nerea Briz Iceta (Inventor)
, Veronica Mora Sanz (Inventor)

Research output: Patent

Abstract

The present invention provides metallic nanocluster (NC) - antibody (Ab) conjugate, wherein the NC has an average size lower than 3 nm and the conjugate: (a) comprises one single NC, (b) the antibody maintains the binding ability; and (c) has a catalytic activity selected from peroxidase-like and photocatalytic activity.The invention also provides a process for the preparation of the conjugate as well as compositions, kits and uses in therapy and diagnostics.Advantageously, the conjugate of the invention shows improved catalytic activity, providing a remarkable improved immunoassay's sensitivity.

Original language	English
Patent number	EP3805760 (A1)
IPC	B82Y15/00\|\|G01N33/58
Priority date	11/10/19
Publication status	Published - 11 Oct 2019

Cite this

@misc{390f326cb8cc45d881a69479ffcf8f14,

title = "Nanocluster-antibody conjugates and uses thereof",

abstract = "The present invention provides metallic nanocluster (NC) - antibody (Ab) conjugate, wherein the NC has an average size lower than 3 nm and the conjugate: (a) comprises one single NC, (b) the antibody maintains the binding ability; and (c) has a catalytic activity selected from peroxidase-like and photocatalytic activity.The invention also provides a process for the preparation of the conjugate as well as compositions, kits and uses in therapy and diagnostics.Advantageously, the conjugate of the invention shows improved catalytic activity, providing a remarkable improved immunoassay's sensitivity.",

author = "\{Briz Iceta\}, Nerea and \{Mora Sanz\}, Veronica",

note = "EP3805760 (A1) EP4042162 (A1) US2023041162 (A1) WO2021069663 (A1); EP3805760 (A1); B82Y15/00||G01N33/58",

year = "2019",

month = oct,

day = "11",

language = "English",

type = "Patent",

}

TY - PAT

T1 - Nanocluster-antibody conjugates and uses thereof

AU - Briz Iceta, Nerea

AU - Mora Sanz, Veronica

N1 - EP3805760 (A1) EP4042162 (A1) US2023041162 (A1) WO2021069663 (A1)

PY - 2019/10/11

Y1 - 2019/10/11

N2 - The present invention provides metallic nanocluster (NC) - antibody (Ab) conjugate, wherein the NC has an average size lower than 3 nm and the conjugate: (a) comprises one single NC, (b) the antibody maintains the binding ability; and (c) has a catalytic activity selected from peroxidase-like and photocatalytic activity.The invention also provides a process for the preparation of the conjugate as well as compositions, kits and uses in therapy and diagnostics.Advantageously, the conjugate of the invention shows improved catalytic activity, providing a remarkable improved immunoassay's sensitivity.

AB - The present invention provides metallic nanocluster (NC) - antibody (Ab) conjugate, wherein the NC has an average size lower than 3 nm and the conjugate: (a) comprises one single NC, (b) the antibody maintains the binding ability; and (c) has a catalytic activity selected from peroxidase-like and photocatalytic activity.The invention also provides a process for the preparation of the conjugate as well as compositions, kits and uses in therapy and diagnostics.Advantageously, the conjugate of the invention shows improved catalytic activity, providing a remarkable improved immunoassay's sensitivity.

UR - https://worldwide.espacenet.com/searchResults?submitted=true&locale=en_EP&DB=EPODOC&ST=advanced&TI=&AB=&PN=EP3805760&AP=&PR=&PD=&PA=&IN=&CPC=&IC=

M3 - Patent

M1 - EP3805760 (A1)

ER -

Nanocluster-antibody conjugates and uses thereof

Abstract

Other files and links

Fingerprint

Cite this