Nanosensor for detection of glucose

Ignacio Del Villar; Ignacio R. Matías; Francisco J. Arregui

doi:10.1117/12.566547

Nanosensor for detection of glucose

Ignacio Del Villar^*
, Ignacio R. Matías
, Francisco J. Arregui

^*Corresponding author for this work

Public University of Navarre

Research output: Contribution to journal › Conference article › peer-review

2 Citations (Scopus)

Abstract

A novel fibre-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme glucose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for estimation of the refractive index of the material deposited and the thickness of bilayers are also given.

Original language	English
Pages (from-to)	259-262
Number of pages	4
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5502
DOIs	https://doi.org/10.1117/12.566547
Publication status	Published - 2004
Externally published	Yes
Event	Second European Workshop on Optical Fibre Sensors, EWOFS'04 - Santander, Spain Duration: 9 Jun 2004 → 11 Jun 2004

Keywords

Biosensors
Chemical sensors
Coupled mode analysis
Electrostatic self-assembly
Glucose
Nanosensors

Access to Document

10.1117/12.566547

Cite this

@article{486d3867390b41e2aa8769998d3ecabf,

title = "Nanosensor for detection of glucose",

abstract = "A novel fibre-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme glucose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for estimation of the refractive index of the material deposited and the thickness of bilayers are also given.",

keywords = "Biosensors, Chemical sensors, Coupled mode analysis, Electrostatic self-assembly, Glucose, Nanosensors",

author = "\{Del Villar\}, Ignacio and Mat{\'i}as, \{Ignacio R.\} and Arregui, \{Francisco J.\}",

year = "2004",

doi = "10.1117/12.566547",

language = "English",

volume = "5502",

pages = "259--262",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Second European Workshop on Optical Fibre Sensors, EWOFS'04 ; Conference date: 09-06-2004 Through 11-06-2004",

}

TY - JOUR

T1 - Nanosensor for detection of glucose

AU - Del Villar, Ignacio

AU - Matías, Ignacio R.

AU - Arregui, Francisco J.

PY - 2004

Y1 - 2004

N2 - A novel fibre-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme glucose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for estimation of the refractive index of the material deposited and the thickness of bilayers are also given.

AB - A novel fibre-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme glucose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for estimation of the refractive index of the material deposited and the thickness of bilayers are also given.

KW - Biosensors

KW - Chemical sensors

KW - Coupled mode analysis

KW - Electrostatic self-assembly

KW - Glucose

KW - Nanosensors

UR - https://www.scopus.com/pages/publications/5544323985

U2 - 10.1117/12.566547

DO - 10.1117/12.566547

M3 - Conference article

AN - SCOPUS:5544323985

SN - 0277-786X

VL - 5502

SP - 259

EP - 262

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Second European Workshop on Optical Fibre Sensors, EWOFS'04

Y2 - 9 June 2004 through 11 June 2004

ER -

Nanosensor for detection of glucose

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this