Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

Carolina Garcia-Vidal; Estela Moreno-García; Marta Hernández-Meneses; Pedro Puerta-Alcalde; Mariana Chumbita; Nicole Garcia-Pouton; Laura Linares; Verónica Rico; Celia Cardozo; José Antonio Martínez; Felipe García; Josep Mensa; Pedro Castro; José María Nicolás; José Muñoz; David Vidal; Alex Soriano; Marta Bodro; Laura Morata; Juan Ambrosioni; Daiana Agüero; Berta Torres; Ana González; Lorena De La Mora; Laura Linares; Fernanda Meira; Irene MacAya; Natalia Rodriguez; David Nicolas; Laia Albiach; Alex Almuedo; Mª Angeles Marcos; Mariana Fernandez-Pittol; Berta Fidalgo; Daniel Camprubí; Catia Cilloniz; Antoni Torres; Adrian Tellez; Sara Fernández; Gemma Sanjuan; Pau Cano; David Caellas

doi:10.1093/cid/ciaa964

Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

Carolina Garcia-Vidal^*
, Estela Moreno-García
, Marta Hernández-Meneses
, Pedro Puerta-Alcalde
, Mariana Chumbita
, Nicole Garcia-Pouton
, Laura Linares
, Verónica Rico
, Celia Cardozo
, José Antonio Martínez
, Felipe García
, Josep Mensa
, Pedro Castro
, José María Nicolás
, José Muñoz
, David Vidal
, Alex Soriano
, Marta Bodro
, Laura Morata
, Juan Ambrosioni

Daiana Agüero, Berta Torres, Ana González, Lorena De La Mora, Laura Linares, Fernanda Meira, Irene MacAya, Natalia Rodriguez, David Nicolas, Laia Albiach, Alex Almuedo, Mª Angeles Marcos, Mariana Fernandez-Pittol, Berta Fidalgo, Daniel Camprubí, Catia Cilloniz, Antoni Torres, Adrian Tellez, Sara Fernández, Gemma Sanjuan, Pau Cano, David Caellas

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR]. 144; 95% confidence interval [CI]. 03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.

Original language	English
Pages (from-to)	127-132
Number of pages	6
Journal	Clinical Infectious Diseases
Volume	74
Issue number	1
DOIs	https://doi.org/10.1093/cid/ciaa964
Publication status	Published - 1 Jan 2022
Externally published	Yes

Keywords

COVID-19
patterns
personalized therapy
pneumonia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/cid/ciaa964

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Garcia-Vidal, C., Moreno-García, E., Hernández-Meneses, M., Puerta-Alcalde, P., Chumbita, M., Garcia-Pouton, N., Linares, L., Rico, V., Cardozo, C., Martínez, J. A., García, F., Mensa, J., Castro, P., Nicolás, J. M., Muñoz, J., Vidal, D., Soriano, A., Bodro, M., Morata, L., ... Caellas, D. (2022). Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019. Clinical Infectious Diseases, 74(1), 127-132. https://doi.org/10.1093/cid/ciaa964

@article{b788bf1543014edea9205fb8cce9beab,

title = "Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019",

abstract = "Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR]. 144; 95\% confidence interval [CI]. 03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.",

keywords = "COVID-19, patterns, personalized therapy, pneumonia",

author = "Carolina Garcia-Vidal and Estela Moreno-Garc{\'i}a and Marta Hern{\'a}ndez-Meneses and Pedro Puerta-Alcalde and Mariana Chumbita and Nicole Garcia-Pouton and Laura Linares and Ver{\'o}nica Rico and Celia Cardozo and Mart{\'i}nez, \{Jos{\'e} Antonio\} and Felipe Garc{\'i}a and Josep Mensa and Pedro Castro and Nicol{\'a}s, \{Jos{\'e} Mar{\'i}a\} and Jos{\'e} Mu{\~n}oz and David Vidal and Alex Soriano and Marta Bodro and Laura Morata and Juan Ambrosioni and Daiana Ag{\"u}ero and Berta Torres and Ana Gonz{\'a}lez and \{De La Mora\}, Lorena and Laura Linares and Fernanda Meira and Irene MacAya and Natalia Rodriguez and David Nicolas and Laia Albiach and Alex Almuedo and \{Angeles Marcos\}, Mª and Mariana Fernandez-Pittol and Berta Fidalgo and Daniel Camprub{\'i} and Catia Cilloniz and Antoni Torres and Adrian Tellez and Sara Fern{\'a}ndez and Gemma Sanjuan and Pau Cano and David Caellas",

year = "2022",

month = jan,

day = "1",

doi = "10.1093/cid/ciaa964",

language = "English",

volume = "74",

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Garcia-Vidal, C, Moreno-García, E, Hernández-Meneses, M, Puerta-Alcalde, P, Chumbita, M, Garcia-Pouton, N, Linares, L, Rico, V, Cardozo, C, Martínez, JA, García, F, Mensa, J, Castro, P, Nicolás, JM, Muñoz, J, Vidal, D, Soriano, A, Bodro, M, Morata, L, Ambrosioni, J, Agüero, D, Torres, B, González, A, De La Mora, L, Linares, L, Meira, F, MacAya, I, Rodriguez, N, Nicolas, D, Albiach, L, Almuedo, A, Angeles Marcos, M, Fernandez-Pittol, M, Fidalgo, B, Camprubí, D, Cilloniz, C, Torres, A, Tellez, A, Fernández, S, Sanjuan, G, Cano, P & Caellas, D 2022, 'Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019', Clinical Infectious Diseases, vol. 74, no. 1, pp. 127-132. https://doi.org/10.1093/cid/ciaa964

TY - JOUR

T1 - Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

AU - Garcia-Vidal, Carolina

AU - Moreno-García, Estela

AU - Hernández-Meneses, Marta

AU - Puerta-Alcalde, Pedro

AU - Chumbita, Mariana

AU - Garcia-Pouton, Nicole

AU - Linares, Laura

AU - Rico, Verónica

AU - Cardozo, Celia

AU - Martínez, José Antonio

AU - García, Felipe

AU - Mensa, Josep

AU - Castro, Pedro

AU - Nicolás, José María

AU - Muñoz, José

AU - Vidal, David

AU - Soriano, Alex

AU - Bodro, Marta

AU - Morata, Laura

AU - Ambrosioni, Juan

AU - Agüero, Daiana

AU - Torres, Berta

AU - González, Ana

AU - De La Mora, Lorena

AU - Linares, Laura

AU - Meira, Fernanda

AU - MacAya, Irene

AU - Rodriguez, Natalia

AU - Nicolas, David

AU - Albiach, Laia

AU - Almuedo, Alex

AU - Angeles Marcos, Mª

AU - Fernandez-Pittol, Mariana

AU - Fidalgo, Berta

AU - Camprubí, Daniel

AU - Cilloniz, Catia

AU - Torres, Antoni

AU - Tellez, Adrian

AU - Fernández, Sara

AU - Sanjuan, Gemma

AU - Cano, Pau

AU - Caellas, David

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR]. 144; 95% confidence interval [CI]. 03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.

AB - Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR]. 144; 95% confidence interval [CI]. 03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.

KW - COVID-19

KW - patterns

KW - personalized therapy

KW - pneumonia

UR - https://www.scopus.com/pages/publications/85143222156

U2 - 10.1093/cid/ciaa964

DO - 10.1093/cid/ciaa964

M3 - Article

C2 - 32649747

AN - SCOPUS:85143222156

SN - 1058-4838

VL - 74

SP - 127

EP - 132

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 1

ER -

Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

Abstract

Keywords

UN SDGs

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