Porous bioactive glass microspheres prepared by flame synthesis process

Jozef Kraxner; Martin Michalek; Acacio Rincon Romero; Hamada Elsayed; Enrico Bernardo; Aldo R. Boccaccini; Dušan Galusek

doi:10.1016/j.matlet.2019.126625

Porous bioactive glass microspheres prepared by flame synthesis process

Jozef Kraxner
, Martin Michalek
, Acacio Rincon Romero
, Hamada Elsayed
, Enrico Bernardo
, Aldo R. Boccaccini
, Dušan Galusek

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

A scaleable, low cost processing method to prepare porous bioactive glass (BG) microspheres is presented. Glass powder with composition based on 45S5 BG and exhibiting irregularly shaped particles was fabricated by conventional melting. Glass powder was alkali activated to induce pore formation during the following flame synthesis step. Porous microspheres, with diameters ranging between 45 and 75 µm, were successfully prepared and characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy with energy-dispersive X-ray spectroscopy. The porous bioactive glass microspheres are promising candidates for applications in bone regeneration, tissue engineering, and as carriers for controlled drug delivery.

Original language	English
Article number	126625
Journal	Materials Letters
Volume	256
DOIs	https://doi.org/10.1016/j.matlet.2019.126625
Publication status	Published - 1 Dec 2019
Externally published	Yes

Keywords

Alkaline activation
Bioactive glass
Flame synthesis
Porous microspheres

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10.1016/j.matlet.2019.126625

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title = "Porous bioactive glass microspheres prepared by flame synthesis process",

abstract = "A scaleable, low cost processing method to prepare porous bioactive glass (BG) microspheres is presented. Glass powder with composition based on 45S5 BG and exhibiting irregularly shaped particles was fabricated by conventional melting. Glass powder was alkali activated to induce pore formation during the following flame synthesis step. Porous microspheres, with diameters ranging between 45 and 75 µm, were successfully prepared and characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy with energy-dispersive X-ray spectroscopy. The porous bioactive glass microspheres are promising candidates for applications in bone regeneration, tissue engineering, and as carriers for controlled drug delivery.",

keywords = "Alkaline activation, Bioactive glass, Flame synthesis, Porous microspheres",

author = "Jozef Kraxner and Martin Michalek and Romero, \{Acacio Rincon\} and Hamada Elsayed and Enrico Bernardo and Boccaccini, \{Aldo R.\} and Du{\v s}an Galusek",

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year = "2019",

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doi = "10.1016/j.matlet.2019.126625",

language = "English",

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TY - JOUR

T1 - Porous bioactive glass microspheres prepared by flame synthesis process

AU - Kraxner, Jozef

AU - Michalek, Martin

AU - Romero, Acacio Rincon

AU - Elsayed, Hamada

AU - Bernardo, Enrico

AU - Boccaccini, Aldo R.

AU - Galusek, Dušan

PY - 2019/12/1

Y1 - 2019/12/1

N2 - A scaleable, low cost processing method to prepare porous bioactive glass (BG) microspheres is presented. Glass powder with composition based on 45S5 BG and exhibiting irregularly shaped particles was fabricated by conventional melting. Glass powder was alkali activated to induce pore formation during the following flame synthesis step. Porous microspheres, with diameters ranging between 45 and 75 µm, were successfully prepared and characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy with energy-dispersive X-ray spectroscopy. The porous bioactive glass microspheres are promising candidates for applications in bone regeneration, tissue engineering, and as carriers for controlled drug delivery.

AB - A scaleable, low cost processing method to prepare porous bioactive glass (BG) microspheres is presented. Glass powder with composition based on 45S5 BG and exhibiting irregularly shaped particles was fabricated by conventional melting. Glass powder was alkali activated to induce pore formation during the following flame synthesis step. Porous microspheres, with diameters ranging between 45 and 75 µm, were successfully prepared and characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy with energy-dispersive X-ray spectroscopy. The porous bioactive glass microspheres are promising candidates for applications in bone regeneration, tissue engineering, and as carriers for controlled drug delivery.

KW - Alkaline activation

KW - Bioactive glass

KW - Flame synthesis

KW - Porous microspheres

UR - https://www.scopus.com/pages/publications/85072172219

U2 - 10.1016/j.matlet.2019.126625

DO - 10.1016/j.matlet.2019.126625

M3 - Article

AN - SCOPUS:85072172219

SN - 0167-577X

VL - 256

JO - Materials Letters

JF - Materials Letters

M1 - 126625

ER -

Porous bioactive glass microspheres prepared by flame synthesis process

Abstract

Keywords

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