Rabdomiolisis por sepsis grave. Discusión de su rol en el desarrollo de falla renal aguda.

C. Videla; G. Hernández; J. Vega; H. Borja

Rabdomiolisis por sepsis grave. Discusión de su rol en el desarrollo de falla renal aguda.

Translated title of the contribution: Rhabdomyolysis caused by severe sepsis: discussion on its role in the development of acute renal failure

C. Videla^*
, G. Hernández
, J. Vega
, H. Borja

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Rhabdomyolysis was evaluated by measurement of total creatine kinase (CK) and lactic dehydrogenase (LDH) in 19 patients with severe sepsis; 12 developed acute renal failure (Group B) and 7 did not (Group A). Results were compared to 7 patients with trauma (Group C) and 6 patients with chronic renal failure and minor infections (Group D). CK was higher (p less than 0.005) in Group B than in A. Results in Group C were similar to those in A. Elevation of CK correlated to increases in creatinine (r = 0.655, p less than 0.005). CK levels of Group D patients were lower than those of Group B. Blood pressure, lactate and pO2 were similar in both groups but thrombopenia was noted in Group B patients. Our results suggest that rhabdomyolysis and thrombopenia play a role in the development of renal failure in patients with severe sepsis.

Translated title of the contribution	Rhabdomyolysis caused by severe sepsis: discussion on its role in the development of acute renal failure
Original language	Spanish
Pages (from-to)	1351-1356
Number of pages	6
Journal	Revista Medica de Chile
Volume	117
Issue number	12
Publication status	Published - Dec 1989
Externally published	Yes

Cite this

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title = "Rabdomiolisis por sepsis grave. Discusi{\'o}n de su rol en el desarrollo de falla renal aguda.",

abstract = "Rhabdomyolysis was evaluated by measurement of total creatine kinase (CK) and lactic dehydrogenase (LDH) in 19 patients with severe sepsis; 12 developed acute renal failure (Group B) and 7 did not (Group A). Results were compared to 7 patients with trauma (Group C) and 6 patients with chronic renal failure and minor infections (Group D). CK was higher (p less than 0.005) in Group B than in A. Results in Group C were similar to those in A. Elevation of CK correlated to increases in creatinine (r = 0.655, p less than 0.005). CK levels of Group D patients were lower than those of Group B. Blood pressure, lactate and pO2 were similar in both groups but thrombopenia was noted in Group B patients. Our results suggest that rhabdomyolysis and thrombopenia play a role in the development of renal failure in patients with severe sepsis.",

author = "C. Videla and G. Hern{\'a}ndez and J. Vega and H. Borja",

year = "1989",

month = dec,

language = "Espa{\~n}ol",

volume = "117",

pages = "1351--1356",

journal = "Revista Medica de Chile",

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TY - JOUR

T1 - Rabdomiolisis por sepsis grave. Discusión de su rol en el desarrollo de falla renal aguda.

AU - Videla, C.

AU - Hernández, G.

AU - Vega, J.

AU - Borja, H.

PY - 1989/12

Y1 - 1989/12

N2 - Rhabdomyolysis was evaluated by measurement of total creatine kinase (CK) and lactic dehydrogenase (LDH) in 19 patients with severe sepsis; 12 developed acute renal failure (Group B) and 7 did not (Group A). Results were compared to 7 patients with trauma (Group C) and 6 patients with chronic renal failure and minor infections (Group D). CK was higher (p less than 0.005) in Group B than in A. Results in Group C were similar to those in A. Elevation of CK correlated to increases in creatinine (r = 0.655, p less than 0.005). CK levels of Group D patients were lower than those of Group B. Blood pressure, lactate and pO2 were similar in both groups but thrombopenia was noted in Group B patients. Our results suggest that rhabdomyolysis and thrombopenia play a role in the development of renal failure in patients with severe sepsis.

AB - Rhabdomyolysis was evaluated by measurement of total creatine kinase (CK) and lactic dehydrogenase (LDH) in 19 patients with severe sepsis; 12 developed acute renal failure (Group B) and 7 did not (Group A). Results were compared to 7 patients with trauma (Group C) and 6 patients with chronic renal failure and minor infections (Group D). CK was higher (p less than 0.005) in Group B than in A. Results in Group C were similar to those in A. Elevation of CK correlated to increases in creatinine (r = 0.655, p less than 0.005). CK levels of Group D patients were lower than those of Group B. Blood pressure, lactate and pO2 were similar in both groups but thrombopenia was noted in Group B patients. Our results suggest that rhabdomyolysis and thrombopenia play a role in the development of renal failure in patients with severe sepsis.

UR - https://www.scopus.com/pages/publications/0024919145

M3 - Artículo

C2 - 2519372

AN - SCOPUS:0024919145

SN - 0034-9887

VL - 117

SP - 1351

EP - 1356

JO - Revista Medica de Chile

JF - Revista Medica de Chile

IS - 12

ER -

Rabdomiolisis por sepsis grave. Discusión de su rol en el desarrollo de falla renal aguda.

Abstract

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