TY - JOUR
T1 - Synthesis of pyridinylpyrrole derivatives via the palladium-catalyzed reaction of acetylpyridines with methyleneaziridines
AU - Siriwardana, Amal I.
AU - Kathriarachchi, Kalum K.A.D.S.
AU - Nakamura, Itaru
AU - Gridnev, Ilya D.
AU - Yamamoto, Yoshinori
PY - 2004/11/3
Y1 - 2004/11/3
N2 - The reaction of methyleneaziridines with o-, m-, and p-acetylpyridines proceeds very smoothly in the presence of a palladium catalyst, affording the biologically very important o-, m-, and p-pyridinylpyrrole derivatives in good to high yields. Not only ortho, meta, and para, but also related substrates, such as acetyl aromatics and hetarenes, can be used as the starting acetyl derivatives to synthesize related compounds to pyridinylpyrrole derivatives.
AB - The reaction of methyleneaziridines with o-, m-, and p-acetylpyridines proceeds very smoothly in the presence of a palladium catalyst, affording the biologically very important o-, m-, and p-pyridinylpyrrole derivatives in good to high yields. Not only ortho, meta, and para, but also related substrates, such as acetyl aromatics and hetarenes, can be used as the starting acetyl derivatives to synthesize related compounds to pyridinylpyrrole derivatives.
UR - https://www.scopus.com/pages/publications/7444240351
U2 - 10.1021/ja0455401
DO - 10.1021/ja0455401
M3 - Article
C2 - 15506731
AN - SCOPUS:7444240351
SN - 0002-7863
VL - 126
SP - 13898
EP - 13899
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 43
ER -