Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response

M. Huerta; E. Sciutto; G. García; N. Villalobos; M. Hernández; G. Fragoso; J. Díaz; A. Díaz; R. Ramírez; S. Luna; J. García; E. Aguilar; S. Espinoza; G. Castilla; J. R. Bobadilla; R. Avila; M. V. José; C. Larralde; A. S. De Aluja

doi:10.1016/S0304-4017(00)00233-8

Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response

M. Huerta^*
, E. Sciutto
, G. García
, N. Villalobos
, M. Hernández
, G. Fragoso
, J. Díaz
, A. Díaz
, R. Ramírez
, S. Luna
, J. García
, E. Aguilar
, S. Espinoza
, G. Castilla
, J. R. Bobadilla
, R. Avila
, M. V. José
, C. Larralde
, A. S. De Aluja

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Vaccination of pigs of mixed genetic make-up, raised as rustically as done in rural Mexico, resulted in effective protection to experimental challenge against Taenia solium cysticercosis. Maximum protection was achieved if pigs were immunized at 70 days of age. There was large variation of viable parasite load within vaccinated pigs and controls, which is suggestive of significant genetic factors influencing susceptibility, besides immunization. Our results strengthen the advisability of pig vaccination for control of T. solium cysticercosis, since it lowers the number of viable cysticerci capable of transforming into tapeworms. (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	209-219
Number of pages	11
Journal	Veterinary Parasitology
Volume	90
Issue number	3
DOIs	https://doi.org/10.1016/S0304-4017(00)00233-8
Publication status	Published - 27 Jun 2000
Externally published	Yes

Keywords

Antibodies
Immunization
Porcine cysticercosis
Taenia solium
Vaccination

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10.1016/S0304-4017(00)00233-8

Cite this

Huerta, M., Sciutto, E., García, G., Villalobos, N., Hernández, M., Fragoso, G., Díaz, J., Díaz, A., Ramírez, R., Luna, S., García, J., Aguilar, E., Espinoza, S., Castilla, G., Bobadilla, J. R., Avila, R., José, M. V., Larralde, C., & De Aluja, A. S. (2000). Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response. Veterinary Parasitology, 90(3), 209-219. https://doi.org/10.1016/S0304-4017(00)00233-8

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title = "Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response",

abstract = "Vaccination of pigs of mixed genetic make-up, raised as rustically as done in rural Mexico, resulted in effective protection to experimental challenge against Taenia solium cysticercosis. Maximum protection was achieved if pigs were immunized at 70 days of age. There was large variation of viable parasite load within vaccinated pigs and controls, which is suggestive of significant genetic factors influencing susceptibility, besides immunization. Our results strengthen the advisability of pig vaccination for control of T. solium cysticercosis, since it lowers the number of viable cysticerci capable of transforming into tapeworms. (C) 2000 Elsevier Science B.V.",

keywords = "Antibodies, Immunization, Porcine cysticercosis, Taenia solium, Vaccination",

author = "M. Huerta and E. Sciutto and G. Garc{\'i}a and N. Villalobos and M. Hern{\'a}ndez and G. Fragoso and J. D{\'i}az and A. D{\'i}az and R. Ram{\'i}rez and S. Luna and J. Garc{\'i}a and E. Aguilar and S. Espinoza and G. Castilla and Bobadilla, \{J. R.\} and R. Avila and Jos{\'e}, \{M. V.\} and C. Larralde and \{De Aluja\}, \{A. S.\}",

year = "2000",

month = jun,

day = "27",

doi = "10.1016/S0304-4017(00)00233-8",

language = "English",

volume = "90",

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Huerta, M, Sciutto, E, García, G, Villalobos, N, Hernández, M, Fragoso, G, Díaz, J, Díaz, A, Ramírez, R, Luna, S, García, J, Aguilar, E, Espinoza, S, Castilla, G, Bobadilla, JR, Avila, R, José, MV, Larralde, C & De Aluja, AS 2000, 'Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response', Veterinary Parasitology, vol. 90, no. 3, pp. 209-219. https://doi.org/10.1016/S0304-4017(00)00233-8

TY - JOUR

T1 - Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico

T2 - Roles of age, genetic background and antibody response

AU - Huerta, M.

AU - Sciutto, E.

AU - García, G.

AU - Villalobos, N.

AU - Hernández, M.

AU - Fragoso, G.

AU - Díaz, J.

AU - Díaz, A.

AU - Ramírez, R.

AU - Luna, S.

AU - García, J.

AU - Aguilar, E.

AU - Espinoza, S.

AU - Castilla, G.

AU - Bobadilla, J. R.

AU - Avila, R.

AU - José, M. V.

AU - Larralde, C.

AU - De Aluja, A. S.

PY - 2000/6/27

Y1 - 2000/6/27

N2 - Vaccination of pigs of mixed genetic make-up, raised as rustically as done in rural Mexico, resulted in effective protection to experimental challenge against Taenia solium cysticercosis. Maximum protection was achieved if pigs were immunized at 70 days of age. There was large variation of viable parasite load within vaccinated pigs and controls, which is suggestive of significant genetic factors influencing susceptibility, besides immunization. Our results strengthen the advisability of pig vaccination for control of T. solium cysticercosis, since it lowers the number of viable cysticerci capable of transforming into tapeworms. (C) 2000 Elsevier Science B.V.

AB - Vaccination of pigs of mixed genetic make-up, raised as rustically as done in rural Mexico, resulted in effective protection to experimental challenge against Taenia solium cysticercosis. Maximum protection was achieved if pigs were immunized at 70 days of age. There was large variation of viable parasite load within vaccinated pigs and controls, which is suggestive of significant genetic factors influencing susceptibility, besides immunization. Our results strengthen the advisability of pig vaccination for control of T. solium cysticercosis, since it lowers the number of viable cysticerci capable of transforming into tapeworms. (C) 2000 Elsevier Science B.V.

KW - Antibodies

KW - Immunization

KW - Porcine cysticercosis

KW - Taenia solium

KW - Vaccination

UR - https://www.scopus.com/pages/publications/0034720836

U2 - 10.1016/S0304-4017(00)00233-8

DO - 10.1016/S0304-4017(00)00233-8

M3 - Article

C2 - 10842001

AN - SCOPUS:0034720836

SN - 0304-4017

VL - 90

SP - 209

EP - 219

JO - Veterinary Parasitology

JF - Veterinary Parasitology

IS - 3

ER -

Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico: Roles of age, genetic background and antibody response

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Keywords

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