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Culturing of neurons in microfluidic arrays

  • L. Griscom
  • , P. Degenaar
  • , M. Denoual
  • , F. Morin
  • ENS Cachan
  • Japan Advanced Institute of Science and Technology
  • The University of Tokyo

Producción científica: Capítulo del libro/informe/acta de congresoContribución a la conferenciarevisión exhaustiva

9 Citas (Scopus)

Resumen

The ability to culture cells on microchips, containing arrays of micro-chambers, is becoming an important diagnostic tool to the biomedical researcher. In this work different neural cell types are cultured in microfluidic arrays made from glass and PDMS substrates.. The microfluidic arrays are made using photolithographically patterned two-layer SU-8 mold and transferred to the PDMS. This allows the creation of interconnected microchambers, which permit physically isolated cells to form axons in preferential directions. The culturing of several different neural cell types was performed using PC-12, P19 and primary culture neural cells. The viability of the cells and integration with microelectrode arrays was tested.

Idioma originalInglés
Título de la publicación alojada2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings
EditoresDavid Beebe, Andre Dittmar
EditorialInstitute of Electrical and Electronics Engineers Inc.
Páginas160-163
Número de páginas4
ISBN (versión digital)0780374800, 9780780374805
DOI
EstadoPublicada - 2002
Publicado de forma externa
Evento2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Madison, Estados Unidos
Duración: 2 may 20024 may 2002

Serie de la publicación

Nombre2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

Conferencia

Conferencia2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology
País/TerritorioEstados Unidos
CiudadMadison
Período2/05/024/05/02

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