Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release

I. Echeverria; I. Silva; M. Gurruchaga; I. Goñi

Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release

I. Echeverria^*
, I. Silva
, M. Gurruchaga
, I. Goñi

^*Autor correspondiente de este trabajo

Producción científica: Capítulo del libro/informe/acta de congreso › Contribución a la conferencia › revisión exhaustiva

Resumen

The ability of acrylic/starch graft copolymers to release drugs in the physiological medium with a release profile was demonstrated which depends on the acrylic component. The preparation of the grafted copolymer was carried out using buthyl methacrylate (BMA) (Merck), hydroxypropyl starch (HS), potato starch (S) (AVEBE) and ceric ammonium nitrate (CAN) (Fluka) as initiator. Grafting was allowed to proceed for 4h. under a constant light source using 149.62 ml of BMA. The release kinetics of the drug was subjected to in vitro dissolution test. The results show that the presence of the branches of PBMA decreases the hydrophilicity.

Idioma original	Inglés
Título de la publicación alojada	Transactions - 7th World Biomaterials Congress
Páginas	1160
Número de páginas	1
Estado	Publicada - 2004
Publicado de forma externa	Sí
Evento	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duración: 17 may 2004 → 21 may 2004

Serie de la publicación

Nombre	Transactions - 7th World Biomaterials Congress

Conferencia

Conferencia	Transactions - 7th World Biomaterials Congress
País/Territorio	Australia
Ciudad	Sydney
Período	17/05/04 → 21/05/04

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@inproceedings{1ce8283e0df8418eb111cfa78de6c1be,

title = "Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release",

abstract = "The ability of acrylic/starch graft copolymers to release drugs in the physiological medium with a release profile was demonstrated which depends on the acrylic component. The preparation of the grafted copolymer was carried out using buthyl methacrylate (BMA) (Merck), hydroxypropyl starch (HS), potato starch (S) (AVEBE) and ceric ammonium nitrate (CAN) (Fluka) as initiator. Grafting was allowed to proceed for 4h. under a constant light source using 149.62 ml of BMA. The release kinetics of the drug was subjected to in vitro dissolution test. The results show that the presence of the branches of PBMA decreases the hydrophilicity.",

author = "I. Echeverria and I. Silva and M. Gurruchaga and I. Go{\~n}i",

year = "2004",

language = "English",

isbn = "1877040193",

series = "Transactions - 7th World Biomaterials Congress",

pages = "1160",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

}

Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release. / Echeverria, I.; Silva, I.; Gurruchaga, M. et al.
Transactions - 7th World Biomaterials Congress. 2004. p. 1160 (Transactions - 7th World Biomaterials Congress).

Producción científica: Capítulo del libro/informe/acta de congreso › Contribución a la conferencia › revisión exhaustiva

TY - GEN

T1 - Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release

AU - Echeverria, I.

AU - Silva, I.

AU - Gurruchaga, M.

AU - Goñi, I.

PY - 2004

Y1 - 2004

N2 - The ability of acrylic/starch graft copolymers to release drugs in the physiological medium with a release profile was demonstrated which depends on the acrylic component. The preparation of the grafted copolymer was carried out using buthyl methacrylate (BMA) (Merck), hydroxypropyl starch (HS), potato starch (S) (AVEBE) and ceric ammonium nitrate (CAN) (Fluka) as initiator. Grafting was allowed to proceed for 4h. under a constant light source using 149.62 ml of BMA. The release kinetics of the drug was subjected to in vitro dissolution test. The results show that the presence of the branches of PBMA decreases the hydrophilicity.

AB - The ability of acrylic/starch graft copolymers to release drugs in the physiological medium with a release profile was demonstrated which depends on the acrylic component. The preparation of the grafted copolymer was carried out using buthyl methacrylate (BMA) (Merck), hydroxypropyl starch (HS), potato starch (S) (AVEBE) and ceric ammonium nitrate (CAN) (Fluka) as initiator. Grafting was allowed to proceed for 4h. under a constant light source using 149.62 ml of BMA. The release kinetics of the drug was subjected to in vitro dissolution test. The results show that the presence of the branches of PBMA decreases the hydrophilicity.

UR - https://www.scopus.com/pages/publications/13844255295

M3 - Conference contribution

AN - SCOPUS:13844255295

SN - 1877040193

SN - 9781877040191

T3 - Transactions - 7th World Biomaterials Congress

SP - 1160

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -

Graft copolymers of starch and butyl methacrylate as biodegradable matrices for controlled drug release

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