TY - GEN
T1 - Integrated polymeric light emitter for disposable photonic lab on chip systems
AU - Carregal-Romero, E.
AU - Ibarlucea, B.
AU - Demming, S.
AU - Büttgenbach, S.
AU - Fernández-Sánchez, C.
AU - Llobera, A.
PY - 2012
Y1 - 2012
N2 - This work presents the monolithic integration of a fluorophore-doped hybrid xerogel polymeric light emitter and a multiple internal reflection configuration (MIR) optofluidic system in a photonic lab on a chip (PhLoC). Two different air mirrors at both sides of the emitter were implemented that improves light coupling into the MIR system. The MIR inner walls were bio-functionalized with a peroxidase enzyme in order to develop a PhLoC analytical system for hydrogen peroxide model target analyte. Absorbance detection of the corresponding enzyme reaction was successfully carried out. The mean sensitivity and limit of detection were calculated to be 0.0119 A.U.μM-1 and 0.73 μM for H2O2, respectively.
AB - This work presents the monolithic integration of a fluorophore-doped hybrid xerogel polymeric light emitter and a multiple internal reflection configuration (MIR) optofluidic system in a photonic lab on a chip (PhLoC). Two different air mirrors at both sides of the emitter were implemented that improves light coupling into the MIR system. The MIR inner walls were bio-functionalized with a peroxidase enzyme in order to develop a PhLoC analytical system for hydrogen peroxide model target analyte. Absorbance detection of the corresponding enzyme reaction was successfully carried out. The mean sensitivity and limit of detection were calculated to be 0.0119 A.U.μM-1 and 0.73 μM for H2O2, respectively.
KW - Absorbance detection
KW - Biofunctionalization
KW - Fluorophore-doped xerogel
KW - Integrated solid-state emitter
UR - https://www.scopus.com/pages/publications/84901811317
M3 - Conference contribution
AN - SCOPUS:84901811317
SN - 9780979806452
T3 - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
SP - 1972
EP - 1974
BT - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PB - Chemical and Biological Microsystems Society
T2 - 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Y2 - 28 October 2012 through 1 November 2012
ER -