TY - JOUR
T1 - Numerically simulated pH-induced reactivation of catalytic activity of horseradish peroxidase
AU - Popović-Bijelić, Ana
AU - Bijelić, Goran
AU - Kolar-Anić, Ljiljana
AU - Vukojević, Vladana
PY - 2005
Y1 - 2005
N2 - A model mechanism that accounts for the experimentally observed pH-dependent enhancement of enzymatic activity of horseradish peroxidase through the catalase-like pathway is proposed. Predictions of the model are tested against a number of experimental results to confirm that kinetic constants used in the numerical simulation are correctly chosen and that the model can be used to emulate the reaction between horseradish peroxidase and hydrogen peroxide in a wide range of conditions.
AB - A model mechanism that accounts for the experimentally observed pH-dependent enhancement of enzymatic activity of horseradish peroxidase through the catalase-like pathway is proposed. Predictions of the model are tested against a number of experimental results to confirm that kinetic constants used in the numerical simulation are correctly chosen and that the model can be used to emulate the reaction between horseradish peroxidase and hydrogen peroxide in a wide range of conditions.
KW - Catalase-like activity
KW - Horseradish peroxidase
KW - Numerical simulations
KW - pH-induced reactivation of catalytic activity
UR - https://www.scopus.com/pages/publications/25144516627
U2 - 10.1196/annals.1342.066
DO - 10.1196/annals.1342.066
M3 - Article
C2 - 16154977
AN - SCOPUS:25144516627
SN - 0077-8923
VL - 1048
SP - 457
EP - 460
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
ER -